Stomach
Other nonneoplastic
Xanthoma
Author: Elliot Weisenberg, M.D.
Last author update: 1 August 2012
Last staff update: 4 April 2023 (update in progress)
Copyright: 2003-2023, PathologyOutlines.com, Inc.
PubMed Search: gastric xanthoma
Table of Contents
Definition / general | Case reports | Gross description | Microscopic (histologic) description | Negative stains | Differential diagnosis | Additional referencesCite this page: Weisenberg E. Xanthoma. PathologyOutlines.com website. https://www.pathologyoutlines.com/topic/stomachxanthoma.html. Accessed June 4th, 2023.
Definition / general
- Also known as xanthelasma, lipid islands
- Common in Japan
- May be due to bile reflux
- No clinical significance
Case reports
- Xanthoma and hyperplastic gastric polyposis (Arch Pathol Lab Med 1989;113:428)
Gross description
- Small yellow / cream colored intramucosal lesion, < 5 mm, single or multiple
Microscopic (histologic) description
- Foamy histiocytes with neutral fat in the lamina propria
Negative stains
- PAS
Differential diagnosis
- Signet ring cell carcinoma
