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General
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Case reports
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Metastases:

Treatment
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Gross description
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Gross images
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Gelatinous tumor attached to atrial septum by narrow pedicle, tumor has irregular surface and nearly fills left atrium

Irregular surface of this left atrial mass caused transient ischemic attacks

Portion of atrial septum and tumor with smooth surface


Cut surface shows marked calcification

Embolism at iliac bifurcation

Emboli of iliac artery

Micro description
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Micro images
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Short cords or syncytia embedded in myxoid matrix

Multilayered rings of myxoma cells around blood vessels are infiltrated by lymphocytes

Scattered spindle cells

Ring structure with 2 cell layers; #3 with atypia


Irregular surface fronds are associated with emboli and younger patient age

Cellular areas near surface

Various images

Blood vessels show mucoid degenerative changes

Central area of bone

Gamna Gandy bodies


Extramedullary hematopoiesis

Thymic rest

Interface with atrial septum often shows lymphoid aggregates, smooth muscle bundles and thick walled vessels

Possible cardiac myxoma (fibrotic mass with myxoma-type cells)


A: CD34+ surface cells
B: CD34+ deep cells
C: factor VIII negative myxoma cells (positive vascular control)
D: smooth muscle actin+



Tumors with glandular component -

Glandular structures


Mucicarmine

Alcian blue (pH 2.5)

CK7

MNF-116


Emboli:

Intramyocardial coronary artery

Pulmonary artery


Positive stains
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Negative stains
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Electron microscopy description
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Electron microscopy images
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Multiple appearing nuclei with little ultrastructural differentiation

Bundles of intermediate filaments and rough endoplasmic reticulum

Primitive intercellular junction without desmosomes

Differential diagnosis
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Additional references
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End of Heart tumor > Cardiac tumors - benign > Myxoma



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