Skin - Nonmelanocytic tumors
Adnexal tumors - hair follicles
Trichilemmoma

Author: Christopher Hale, M.D. (see Authors page)

Revised: 6 October 2016, last major update June 2012

Copyright: (c) 2002-2016, PathologyOutlines.com, Inc.

PubMed Search: Trichilemmoma [title]

See also: Trichilemmal carcinoma

Cite this page: Trichilemmoma. PathologyOutlines.com website. http://www.pathologyoutlines.com/topic/skintumornonmelanocytictrichilemmoma.html. Accessed December 11th, 2016.
Definition / General
  • Also called tricholemmoma
  • Benign
  • Derived from the outer root sheath of hair follicle
  • Cowden's syndrome: multiple trichilemmomas, multiple hamartomas in skin, oral mucosa, breast, thyroid and intestines, as well as malignancies at these sites
Clinical Images

Images hosted on PathOut server:

Knee, courtesy of Mark R. Wick, M.D.

Gross Description
  • Warty papule on face
Micro Description
  • Lobular or plate-like growth of pale pink, glassy cells
  • Often palisading at periphery, thickened basement membrane, occasional central keratinization
  • Desmoplastic variant simulates malignancy
Micro Images

Images hosted on PathOut server:

Courtesy of Mark R. Wick, M.D.



Images hosted on Flickr:

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Differential Diagnosis