Other benign tumors


Topic Completed: 1 April 2010

Minor changes: 26 August 2020

Copyright: 2002-2021,, Inc.

PubMed Search: Leiomyoma [title] breast

Hind Warzecha, M.D.
Page views in 2020: 1,361
Page views in 2021 to date: 1,068
Cite this page: Warzecha H. Leiomyoma. website. Accessed October 25th, 2021.
Definition / general
  • Benign smooth muscle tumor similar to counterparts elsewhere
  • Rare in breast
  • Usually involves nipple
Clinical features
Case reports
  • Complete excision to prevent recurrence
Clinical images

Contributed by Dr. Mark R. Wick

Breast skin

Gross description
  • Often ill defined
Microscopic (histologic) description
  • Interlacing bundles of spindle cells with eosinophilic cytoplasm and blunt ended, cigar shaped nuclei
  • May have epithelioid or granular features
  • No atypia, no hypercellularity, no / rare mitotic figures ( < 3 per 10 HPF), no necrosis
Microscopic (histologic) images

AFIP images

Circumscribed tumor of spindled cells without atypia

 Contributed by Dr. Mark R. Wick

Breast skin

Negative stains
Differential diagnosis
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