Skin nonmelanocytic tumor
Fibrous, fibrohistiocytic and myofibroblastic neoplasms
Dermatomyofibroma
Author: Christopher S. Hale, M.D.
Last author update: 1 September 2012
Last staff update: 16 April 2021
Copyright: 2003-2023, PathologyOutlines.com, Inc.
PubMed search: Dermatomyofibroma [title]
Table of Contents
Definition / general | Case reports | Clinical images | Gross description | Microscopic (histologic) description | Microscopic (histologic) images | Positive stains | Negative stains | Differential diagnosisCite this page: Hale CS. Dermatomyofibroma. PathologyOutlines.com website. https://www.pathologyoutlines.com/topic/skintumornonmelanocyticdermatomyofibroma.html. Accessed June 9th, 2023.
Definition / general
- Distinct cutaneous plaque-like proliferation of fibroblasts and myofibroblasts (J Cutan Pathol 1992;19:85, Br J Dermatol 1993;129:69)
- Also called cutaneous myofibroma
- Women > men, usually age 20 - 39, but occasionally in children (J Cutan Pathol 2011;38;967)
- Upper arms, neck or trunk
- Pediatric cases more often in neck
Case reports
- 4 month old boy with development of dermatomyofibroma (Ann Dermatol 2011;23:S72)
- Two young women with dermatomyofibroma (J Cutan Pathol 1994;21:371)
Clinical images
Contributed by Mark R. Wick, M.D.
Images hosted on other servers:
Ill defined bluish firm plaque on the left flank
Gross description
- Reddish brown plaque or nodule
Microscopic (histologic) description
- Fascicles of monomorphic spindle cells parallel to epidermis
Microscopic (histologic) images
Contributed by Mark R. Wick, M.D.
Breast skin
Soft tissue
MSA stain
Images hosted on other servers:
H&E and smooth muscle actin
Positive stains
Negative stains
Differential diagnosis
- Dermatofibroma
- Diffuse neurofibroma
- Keloid (gross)
- Plaque stage DFSP
- Other tumors with myofibroblastic differentiation
