Stomach
Gastritis
Atrophic gastritis
Author: Elliot Weisenberg, M.D.
Last author update: 1 August 2012
Last staff update: 26 September 2023 (update in progress)
Copyright: 2003-2023, PathologyOutlines.com, Inc.
PubMed Search: chronic (atrophic) gastritis
Cite this page: Weisenberg E. Atrophic gastritis. PathologyOutlines.com website. https://www.pathologyoutlines.com/topic/stomachchronicatrophic.html. Accessed September 30th, 2023.
Definition / general
- Sometimes known as multifocal atrophic gastritis; formerly environmental gastritis
- Chronic gastritis accompanied by glandular atrophy (mild, moderate, severe), usually secondary to chronic H. pylori infection
- Initially glands are compressed, later they are destroyed, loss of acid leads to conditions conducive to bacterial growth
- Associated with duodenal ulcer, gastric peptic ulcer
- Degree of atrophy and intestinal metaplasia are correlated (Hum Pathol 2001;32:31)
- Epithelial changes may become dysplastic and progress to carcinoma
Gross description
- Thin, smooth mucosa (without rugae), prominent submucosal vessels (due to mucosal atrophy)
