Stomach
Lymphoma
Lymphoma-general
Author: Elliot Weisenberg, M.D.
Last author update: 1 September 2012
Last staff update: 1 September 2020
Copyright: 2003-2023, PathologyOutlines.com, Inc.
PubMed Search: stomach lymphoma
Cite this page: Weisenberg E. Lymphoma-general. PathologyOutlines.com website. https://www.pathologyoutlines.com/topic/stomachlymphomageneral.html. Accessed June 2nd, 2023.
Definition / general
- 55 - 75% of primary gastrointestinal lymphomas are gastric
- Lymphomas are 1 - 7% of gastric malignancies
- Diffuse large B-cell lymphoma most common, then extranodal marginal zone (MALT) lymphoma
- Most patients age 60+
- Clinically resembles carcinoma, but usually better prognosis
- Associated with erosion (61%), intestinal metaplasia (59%), H. pylori (57%), atrophy (37%), dysplasia (4%) (Arch Pathol Lab Med 2000;124:1628)
Microscopic (histologic) description
- Diffuse large B-cell lymphoma generally resembles nodal disease
- Features highly suggestive of low grade lymphoma versus inflammation are dense lymphoid infiltrates with either prominent lymphoepithelial lesions, moderate cytologic atypia or Dutcher bodies (Am J Surg Pathol 1990;14:1087)
