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Table of contents

General: primary referenceshemostasis-generalnormal hemostasisintrinsic pathwayextrinsic pathwaycommon pathwayprotein C/Sthrombomodulinantithrombinfibrinolysis pathwaycontact system

Bleeding disorders: generallaboratory approach

Acquired bleeding disorders: acute phase reactionacquired dysfibrinogenemiaacquired von Willebrand diseaseamyloidosisbovine coagulation factor inhibitorsDICfactor V inhibitorfactor VIII inhibitorinhibitors in nonhemophilia patientsfactor IX inhibitorliver dysfunctionlupus anticoagulantsproteinuriaVitamin K deficiency/warfarin

Hereditary bleeding disorders: generalalgorithm for workupfactor I (fibrinogen) deficiencyfactor II (prothrombin) deficiencyfactor V deficiencyfactor VII deficiencyfactor VIII deficiency (hemophilia A)factor IX deficiency (hemophilia B) factor X deficiencyfactor XI deficiencyfactor XII deficiencyfactor XIII deficiencyhigh molecular weight kininogen deficiencyprekallifrein deficiencyvon Willebrand disease

Therapy related coagulopathies: warfarindanaparoidheparin heparin-low molecular weighthirudinthrombolytic therapy

Acquired thrombophilia / hypercoagulopathies: generalantiphospholipid antibodiesheparin induced thrombocytopenia

Hereditary thrombophilia / hypercoagulopathies: generalactivated protein C resistance / Factor V Leidenantithrombin deficiencydysfibrinogenemiaelevated coagulation factorsheparin cofactor II deficiencyhyperhomocysteinemiaprotein C deficiencyprotein S deficiencyprothrombin gene mutation (G20210A)sickle cell disease

Coagulation laboratory tests: generalquality assuranceabnormal PT and PTTactivated clotting timeactivated protein C resistance / Factor V Leidenanticardiolipin antibodiesantiplasminantithrombin bleeding timeclot retractioncryoglobulin / cryofibrinogenD-dimerdabigatranecarin clotting timefactor assaysfactor I (fibrinogen) assayfactor V Leidenfactor VII assayfactor VIII assayfactor VIII inhibitorfactor IX assayfactor Xa assayfactor XI assayfactor XIII assayheparin induced thrombocytopeniaheparinasehigh molecular weight kininogenhomocysteinehypercoagulation panelINRInternational sensitivity indexlow molecular weight heparinlupus anticoagulantmixing studiesplasminogen assayplasminogen activator antigen-1 (PAI1)platelet aggregation studiesplatelet antibodiesplatelet hyperaggregation studiesprekallikrein assayprotein C assaysprotein S assaysprothrombin gene 20210APTaPTTreptilase timethrombin timetPAvWF testing-generalvWF antigen analysisvWF activityvWF multimer analysis

Superpages: entire chapter

Alphabetical table of contents

A-E: abnormal PT and PTT testingacquired dysfibrinogenemiaacquired thrombophilia / hypercoagulopathies-generalacquired von Willebrand diseaseactivated clotting timeactivated protein C resistance / Factor V Leidenactivated protein C resistance / Factor V Leiden testingacute phase reactionamyloidosisanticardiolipin antibody testingantiphospholipid antibodiesantiplasmin testingantithrombinantithrombin deficiencyantithrombin testing aPTT testingbleeding disorders-generalbleeding disorders-laboratory approachbleeding timebovine coagulation factor inhibitorsclot retraction testingcoagulation laboratory tests-generalcommon pathwaycontact systemcryoglobulin / cryofibrinogen testingD-dimer testingdabigatran testingdanaparoidDICdysfibrinogenemiaecarin clotting timeelevated coagulation factorsextrinsic pathway

F: factor assaysfactor I (fibrinogen) assayfactor I (fibrinogen) deficiencyfactor II (prothrombin) deficiencyfactor V deficiencyfactor V inhibitorfactor V Leiden testingfactor VII assayfactor VII deficiencyfactor VIII assayfactor VIII deficiency (hemophilia A)factor VIII inhibitorfactor VIII inhibitor testingfactor IX assayfactor IX deficiency (hemophilia B) factor IX inhibitorfactor X deficiencyfactor Xa assayfactor XI assayfactor XI deficiencyfactor XII deficiencyfactor XIII assayfactor XIII deficiencyfibrinolysis pathway

G-N: hemostasis-generalheparinheparin cofactor II deficiencyheparin induced thrombocytopeniaheparin induced thrombocytopenia testingheparin-low molecular weightheparinase testinghereditary bleeding disorders-algorithm for workuphereditary bleeding disorders-generalhereditary thrombophilia / hypercoagulopathies-generalhigh molecular weight kininogen deficiencyhigh molecular weight kininogen testinghirudinhomocysteine testinghypercoagulation panelhyperhomocysteinemiainhibitors in nonhemophilia patientsINR testingInternational sensitivity indexintrinsic pathwayliver dysfunctionlow molecular weight heparin testinglupus anticoagulant testinglupus anticoagulantsmixing studiesnormal hemostasis

O-Z: plasminogen activator antigen-1 (PAI1) testingplasminogen assayplatelet aggregation studiesplatelet antibodiesplatelet hyperaggregation studiesprekallikrein assayprekallifrein deficiencyprimary referencesprotein C / S-normalprotein C assaysprotein C deficiencyprotein S assaysprotein S deficiencyproteinuriaprothrombin gene 20210A testingprothrombin gene mutation (G20210A)PT testingquality assurancereptilase timesickle cell diseasethrombin timethrombolytic therapythrombomodulintPA testingVitamin K deficiency/warfarinvon Willebrand diseasevWF testing-generalvWF antigen analysisvWF activityvWF multimer analysiswarfarin

Primary references
top

Consultative Hemostasis and Thrombosis: Elsevier, 2007
Massachusetts General Hospital handbook


Recent Coagulation books

Antovic: 2013

Bennett: 2014

Blomback: 2010

Ciesla: 2011

Gulati: 2012

Hillman: 2010

Key: 2009

Kitchen: 2009

Kottke-Marchant: 2008

Laposata: 2010

Lichtman: 2011

Ma: 2012

Shaz: 2013



Click here for other Coagulation / Transfusion Medicine and here for Hematology books


End of Coagulation chapter


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