Ovary

• Presence of ectopic decidualized uterine stromal cells in the ovary

• Presence of ectopic decidualized uterine stromal cells in the ovary
• Usually an incidental finding associated with pregnancy
• Typically transient, will regress 4 - 6 weeks postpartum

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Contributed by Aurelia Busca, M.D., Ph.D.

Which of the following is true about the ovarian change illustrated in the figure shown above?

1. It is a malignant process
2. It is only seen in the ovary
3. It requires lymph node sampling and full staging for management
4. More sampling is required to demonstrate the presence of glands
5. Typically associated with pregnancy

E. Typically associated with pregnancy. The image shows ovarian deciduosis, which is associated with pregnancy, is typically transient and resolves postpartum. Answer A is incorrect because ovarian deciduosis is a benign process typically associated with pregnancy. Answer D is incorrect because it consists of stromal tissue, without glands. Answer C is incorrect because it typically regresses after pregnancy and does not require treatment. Answer B is incorrect because deciduosis can be seen at other sites (cervix, peritoneal cavity, etc.).

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Reference: Ectopic decidual reaction

Which of the following is true about ovarian deciduosis?

1. It can be mistaken for endometriosis
2. It is CD10 negative by immunohistochemistry
3. Presence of nuclear atypia indicates malignant potential
4. Responds to chemotherapy
5. Treatment includes resection with or without chemotherapy

A. It can be mistaken for endometriosis with stromal decidualization but unlike endometriosis, it does not contain glands. Answer B is incorrect because both have CD10 positive stroma. Answers C, D and E are incorrect because ovarian deciduosis is a benign incidental process and does not require treatment.

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Reference: Ectopic decidual reaction