Skin nonmelanocytic tumor
Fibrous, fibrohistiocytic and myofibroblastic neoplasms
Fibroepithelial polyp


Topic Completed: 1 May 2015

Minor changes: 1 October 2020

Copyright: 2002-2020, PathologyOutlines.com, Inc.

PubMed Search: Fibroepithelial polyp [title]

Hillary Rose Elwood, M.D.
Page views in 2019: 41,872
Page views in 2020 to date: 31,014
Cite this page: Elwood H. Fibroepithelial polyp. PathologyOutlines.com website. https://www.pathologyoutlines.com/topic/skintumornonmelanocyticfibroepithelialpolyp.html. Accessed October 24th, 2020.
Definition / general
  • Also known as acrochordon, skin tag, soft fibroma, cutaneous papilloma, cutaneous tag, fibroma pendulum, fibroma molluscum
  • Common, benign skin lesion of adults
  • Usually occur on intertriginous areas (i.e. axilla, groin), face, neck, eyelids
  • Associated with diabetes, abnormal lipid profile, other components of metabolic syndrome (Eur J Dermatol 2012;22:106)
  • Multiple lesions can be seen in Birt-Hogg-Dube syndrome
  • May increase in number during pregnancy
Clinical features
  • Soft papilloma, flesh colored to dark brown, sessile to pedunculated
  • A few millimeters to multiple centimeters in size
  • Larger lesions often attach to skin by slender stalks
Prognosis and treatment
  • Benign lesions, excised for cosmetic reasons
Case reports
Clinical images

Images hosted on other servers:
Penile fibroepithelial polyp

Penile fibroepithelial polyp

Fibroepithelial polyp<br>at posterior wall of<br>external auditory canal

Fibroepithelial polyp
at posterior wall of
external auditory canal

Microscopic (histologic) description
  • Fibrovascular cores covered by squamous epithelium
  • Larger lesions may have a flattened epidermis
  • Smaller lesions can have epidermal hyperplasia or seborrheic keratosis-like changes
  • Central core composed of loose collagen with increased blood vessels
  • In larger lesion, may have a central core of adipose tissue
  • Pagetoid dyskeratosis is sometimes present as an incidental finding
  • May have ischemic necrosis due to torsion
Microscopic (histologic) images

Images hosted on other servers:
Acrochordon

Acrochordon

Edematous stroma

Edematous stroma

Stellate fibroblasts

Stellate fibroblasts

Dermal edema

Dermal edema

Keratinized squamous epithelium

Keratinized squamous epithelium

Epidermis with hyperkeratosis

Epidermis with hyperkeratosis

Differential diagnosis
Back to top
Image 01 Image 02