Lymph nodes - not lymphoma
Inclusions, pigment, ectopic cells or tissue
Reviewer: William D. DePond, M.D. (see Reviewers page)
Revised: 3 July 2013, last major update June 2006
Copyright: (c) 2003-2013, PathologyOutlines.com, Inc.
- Portal lymphadenopathy due to lipofuscin pigment is associated with primary biliary cirrhosis and other chronic cholestatic conditions (J Clin Pathol 1989;42:1160)
- Lipofuscin pigment present in sinus histiocytes
Left - portal lymph node shows expansion of medullary sinuses due to brown pigment
Right - sinus histiocytes contain variably sized granules positive for lipofuscin with Long Ziehl-Neelsen stain
Electron microscopy images
Lipofuscin granules in cardiomyocytes
End of Lymph nodes - not lymphoma > Inclusions, pigment, ectopic cells or tissue > Lipofuscin
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