Breast malignant, males, children
Miscellaneous
Staging of breast carcinoma (AJCC 8th Edition)

Author: Nat Pernick, M.D. (see Authors page)

Revised: 10 October 2017, last major update October 2017

Copyright: (c) 2001-2017, PathologyOutlines.com, Inc.

PubMed Search: staging breast carcinoma
Cite this page: Staging of breast carcinoma (AJCC Eighth Edition). PathologyOutlines.com website. http://www.pathologyoutlines.com/topic/breastmalignantstaging.html. Accessed October 20th, 2017.
Definition / general
Changes from the seventh edition
  • Use of IHC for important tumor markers is incorporated into staging to refine prognosis
  • Genomic assays are used to downstage some estrogen receptor positive, lymph node negative tumors
  • LCIS is no longer classified as Tis because it is considered a risk factor, not a malignancy
  • A summary of changes in the eighth edition is listed in Table 1
Primary tumor (T)
Regional lymph nodes (N)
  • Note: ITC means isolated tumor cells
  • See Table 3
Distant metastasis (M)
TNM Anatomic Stage Groups
  • See Table 5
  • Note: This table should only be used in global regions where biomarker tests are not routinely available; cancer registries in the US must use the Prognostic Stage Group table described in the article
Additional references