Inflammatory / infectious / autoimmune / systemic disorders

Inflammatory aural / otic polyp

Last author update: 1 October 2013
Last staff update: 24 May 2023

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PubMed Search: Inflammatory aural polyp

Nat Pernick, M.D.
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Cite this page: Pernick N. Inflammatory aural / otic polyp. PathologyOutlines.com website. https://www.pathologyoutlines.com/topic/earinflammatoryotic.html. Accessed June 3rd, 2023.
Definition / general
  • Inflammatory polypoid proliferation of middle ear mucosa secondary to chronic otitis media
  • May perforate tympanic membrane and appear to originate from external auditory canal; with time, may destroy ossicles
  • More common in children but occurs in all ages
  • Often associated with extensive disease of mastoid air cell system (in rural India, Am J Otolaryngol 2003;24:155) or cholesteatoma of middle ear (Acta Otorrinolaringol Esp 2003;54:161)
  • Excision
  • Possibly mastoid exploration
Gross description
  • Polypoid, soft / rubbery, pink / tan / red lesion
Microscopic (histologic) description
  • Squamous or ciliated columnar epithelium containing lymphocytes, histiocytes, plasma cells, eosinophils
  • Mott cells (plasma cells with large eosinophilic immunoglobulin) and granulation type tissue; usually mast cells (J Laryngol Otol 1995;109:491), variable neutrophils, multinucleated giant cells, cholesterol granulomas and tympanosclerosis
Differential diagnosis
  • Plasmacytoma: monoclonal light chains
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