Table of Contents
Definition / general | Treatment | Gross description | Gross images | Microscopic (histologic) description | Microscopic (histologic) imagesCite this page: Ehdaivand S. Leydig cell tumor. PathologyOutlines.com website. https://www.pathologyoutlines.com/topic/ovarytumorleydig.html. Accessed May 30th, 2023.
Definition / general
- Rare, derived from hilar cells
- Almost always benign
- Call a nonhilar Leydig cell tumor if it occurs in ovarian cortical stroma
- Symptoms: virilization, elevated 17-ketosteroid excretion and unresponsive to cortisol suppression
Treatment
- Excision
Gross description
- Unilateral
Gross images
AFIP images
Red-brown mass
Brown-black nodule
Microscopic (histologic) description
- Large lipid laden cells with distinct borders; Reinke crystals common
Microscopic (histologic) images
AFIP images
Crystals of Reinke
Separated cellular areas
Prominent fibrous stroma
Fibrinoid replacement
Abundant, pale, vacuolated cytoplasm
Enlarged, hyperchromatic, bizarre nuclei
