Skin nonmelanocytic tumor
Adnexal tumors
Sweat gland derived (apocrine & eccrine glands)
Syringocystadenoma papilliferum


Topic Completed: 1 June 2012

Minor changes: 16 October 2020

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PubMed Search: Syringocystadenoma papilliferum [title]

Christopher S. Hale, M.D.
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Cite this page: Hale C. Syringocystadenoma papilliferum. PathologyOutlines.com website. https://www.pathologyoutlines.com/topic/skintumornonmelanocyticpapillarysyringadenoma.html. Accessed October 26th, 2020.
Definition / general
  • Also known as papillary syringadenoma
  • Warty tumor of scalp, neck and face that occurs at any age
  • Slow growing or a recent change in an apparent birthmark
  • 1/3 have adjacent nevus sebaceus, 10% have adjacent basal cell carcinoma
  • Eccrine syringofibroadenoma: with prominent fibrous stroma
  • Syringocystadenocarcinoma papilliferum: malignant counterpart
Clinical images

Images hosted on other servers:

Syringocystadenoma
papilliferum

Microscopic (histologic) description
  • Glandular papillary proliferation connected to skin surface, dense plasma cell infiltrate
Microscopic (histologic) images

Contributed by Joel Pinczewski M.D., Ph.D.

Syringocystadenoma papilliferum



Contributed by Okechukwu Okafor, Ph.D.

Ulcerated scalp mass of 20 years duration



Images hosted on other servers:

Apocrine

Positive stains
  • Plasma cells are IgA+, IgG+
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