Skin nonmelanocytic tumor
Adnexal tumors
Sweat gland derived (apocrine & eccrine glands)
Syringocystadenoma papilliferum

Topic Completed: 1 June 2012

Minor changes: 16 October 2020

Copyright: 2002-2021,, Inc.

PubMed Search: Syringocystadenoma papilliferum [title]

Christopher S. Hale, M.D.
Page views in 2020: 11,815
Page views in 2021 to date: 732
Cite this page: Hale C. Syringocystadenoma papilliferum. website. Accessed January 22nd, 2021.
Definition / general
  • Also known as papillary syringadenoma
  • Warty tumor of scalp, neck and face that occurs at any age
  • Slow growing or a recent change in an apparent birthmark
  • 1/3 have adjacent nevus sebaceus, 10% have adjacent basal cell carcinoma
  • Eccrine syringofibroadenoma: with prominent fibrous stroma
  • Syringocystadenocarcinoma papilliferum: malignant counterpart
Clinical images

Images hosted on other servers:


Microscopic (histologic) description
  • Glandular papillary proliferation connected to skin surface, dense plasma cell infiltrate
Microscopic (histologic) images

Contributed by Joel Pinczewski M.D., Ph.D.

Syringocystadenoma papilliferum

Contributed by Okechukwu Okafor, Ph.D.

Ulcerated scalp mass of 20 years duration

Images hosted on other servers:


Positive stains
  • Plasma cells are IgA+, IgG+
Back to top
Image 01 Image 02