Skin nonmelanocytic tumor
Adnexal tumors - eccrine sweat glands
Aggressive digital papillary adenoma

Topic Completed: 1 June 2012

Revised: 4 April 2019

Copyright: 2002-2016,, Inc.

PubMed Search: Aggressive digital papillary adenoma

Christopher S. Hale, M.D.
Page views in 2018: 1,627
Page views in 2019 to date: 1,826
Cite this page: Hale C. Aggressive digital papillary adenoma. website. Accessed December 14th, 2019.
Definition / general
  • Also called digital papillary eccrine adenoma
  • Usually digits
  • Recurs locally
  • Histologic criteria not reliable for distinguishing from digital papillary adenocarcinoma (Modern Pathol 2006;19:S93)
  • Malignant counterpart has poor glandular differentiation, necrosis, atypia, invasion
  • Metastasizes to lung in many cases
Case reports
Microscopic (histologic) description
  • Tubuloalveolar and ductal structures
  • Also areas of papillary projections protruding into lumina (may resemble breast carcinoma)
Positive stains
Differential diagnosis
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