Skin nonmelanocytic tumor
Adnexal tumors - eccrine sweat glands
Digital papillary adenocarcinoma



Topic Completed: 1 June 2012

Minor changes: 24 February 2020

Copyright: 2002-2020, PathologyOutlines.com, Inc.

PubMed Search: Digital papillary adenocarcinoma

Christopher S. Hale, M.D.
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Cite this page: Hale C. Digital papillary adenocarcinoma. PathologyOutlines.com website. http://www.pathologyoutlines.com/topic/skintumornonmelanocyticaggressivedigital.html. Accessed May 30th, 2020.
Definition / general
  • Also called digital papillary eccrine adenoma, aggressive digital papillary adenoma
  • Usually digits
  • Recurs locally
  • Histologic criteria not reliable for distinguishing from digital papillary adenocarcinoma (Modern Pathol 2006;19:S93)
  • Malignant counterpart has poor glandular differentiation, necrosis, atypia, invasion
  • Metastasizes to lung in many cases
Case reports
Microscopic (histologic) description
  • Tubuloalveolar and ductal structures
  • Also areas of papillary projections protruding into lumina (may resemble breast carcinoma)
Positive stains
Differential diagnosis
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