Germ cell tumors

Embryonal carcinoma

Topic Completed: 1 December 2012

Minor changes: 21 October 2020

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PubMed search: Ovarian embryonal carcinoma

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Cite this page: Ehdaivand S. Embryonal carcinoma. PathologyOutlines.com website. https://www.pathologyoutlines.com/topic/ovarytumorembryonal.html. Accessed October 20th, 2021.
Definition / general
  • Similar to testicular embryonal carcinoma
  • Median age 15 years, patients often present with precocious puberty, also vaginal bleeding, amenorrhea and hirsutism
  • Serum hCG always high (positive pregnancy test), AFP sometimes high
Gross description
  • Median 17 cm, smooth and glistening, variegated cut surface with extensive hemorrhage and necrosis
Microscopic (histologic) description
  • Sheets and nests of large primitive cells, occasional papillae and abortive glands
  • Syncytiotrophoblast-like tumor cells seen (hCG+)
Microscopic (histologic) images

AFIP images

Papillary pattern

Irregular slit-like spaces

Solid aggregates

giant cells (SGCs)

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