Cite this page: Pernick N. Myeloperoxidase. PathologyOutlines.com website. https://www.pathologyoutlines.com/topic/stainsmyeloperoxidase.html. Accessed February 3rd, 2023.
Definition / general
- Staining is either immunohistochemistry (IHC) or enzyme cytochemistry - enzyme cytochemistry is most sensitive and specific stain for myeloid leukemias and granulocytic sarcoma
- Stains neutrophils strongly (diffuse granular pattern), other granulocytes variably
Positive staining - normal
- Neutrophils, eosinophils, monocytes (variable), AML-M1, M2, microgranular M3
- Granulocytic sarcoma
- Lymphocytes, ALL