Stains & CD markers

Topic Completed: 1 June 2005

Minor changes: 21 June 2021

Copyright: 2002-2022,, Inc.

PubMed Search: Myeloperoxidase [title]

Nat Pernick, M.D.
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Cite this page: Pernick N. Myeloperoxidase. website. Accessed January 21st, 2022.
Definition / general
  • Staining is either immunohistochemistry (IHC) or enzyme cytochemistry - enzyme cytochemistry is most sensitive and specific stain for myeloid leukemias and granulocytic sarcoma
  • Stains neutrophils strongly (diffuse granular pattern), other granulocytes variably
Positive staining - normal
  • Neutrophils, eosinophils, monocytes (variable), AML-M1, M2, microgranular M3
  • Granulocytic sarcoma
Negative staining
  • Lymphocytes, ALL
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