Stomach

Gastritis

Gastritis-features to report



Topic Completed: 1 July 2012

Minor changes: 15 July 2020

Copyright: 2003-2019, PathologyOutlines.com, Inc.

PubMed Search: features to report gastritis

Elliot Weisenberg, M.D.
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Table of Contents
Definition / general
Cite this page: Weisenberg E. Gastritis-features to report. PathologyOutlines.com website. https://www.pathologyoutlines.com/topic/stomachgastritisfeatures.html. Accessed November 29th, 2021.
Definition / general
  • Sydney system
    • Biopsies:
      • Recommended to take 5 biopsy specimens, 2 from antrum (both at 2 to 3 cm from the pylorus, 1 from lesser and 1 from greater curvature), 2 from corpus (both at 8 cm from the cardia, from lesser and greater curvature), 1 from the incisura angularis
      • All samples should be identified and studied separately
      • 5 biopsies appears to be adequate, although site is often misidentified
      • The Sydney system guidelines technically should only be applied when all 5 biopsy sites are submitted for examination (Hum Pathol 2003;34:28)
      • Low concordance rate between pathologists improves after joint review of cases (Hum Pathol 1999;30:1431)
      • Proposed new system for staging and grading (Hum Pathol 2005;36:228)

    • Report:
      • Location of gastritis (antrum, fundus / body, cardia, diffuse)
      • Type of gastritis: active, chronic or other (lymphocytic, granulomatous, eosinophilic, etc.)
      • Grade the presence of Helicobacter pylori, chronic inflammation, active inflammation, glandular atrophy, intestinal metaplasia
      • Report (ungraded) granulomas, eosinophils, intraepithelial lymphocytes
      • Special stain to detect H. pylori is recommended when inflammation is present

    • Alternative reporting:
      • Antral predominant, corpus predominant or pangastritis
      • Focal or diffuse
      • Superficial or full thickness
      • Atrophy: present or absent
      • Metaplasia: present or absent
      • Inflammation: active, chronic or both
      • H. pylori present or absent
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