Table of Contents
Definition / generalCite this page: Weisenberg E. Gastritis-features to report. PathologyOutlines.com website. https://www.pathologyoutlines.com/topic/stomachgastritisfeatures.html. Accessed September 26th, 2023.
Definition / general
- Sydney system
- Biopsies:
- Recommended to take 5 biopsy specimens, 2 from antrum (both at 2 to 3 cm from the pylorus, 1 from lesser and 1 from greater curvature), 2 from corpus (both at 8 cm from the cardia, from lesser and greater curvature), 1 from the incisura angularis
- All samples should be identified and studied separately
- 5 biopsies appears to be adequate, although site is often misidentified
- The Sydney system guidelines technically should only be applied when all 5 biopsy sites are submitted for examination (Hum Pathol 2003;34:28)
- Low concordance rate between pathologists improves after joint review of cases (Hum Pathol 1999;30:1431)
- Proposed new system for staging and grading (Hum Pathol 2005;36:228)
- Report:
- Location of gastritis (antrum, fundus / body, cardia, diffuse)
- Type of gastritis: active, chronic or other (lymphocytic, granulomatous, eosinophilic, etc.)
- Grade the presence of Helicobacter pylori, chronic inflammation, active inflammation, glandular atrophy, intestinal metaplasia
- Report (ungraded) granulomas, eosinophils, intraepithelial lymphocytes
- Special stain to detect H. pylori is recommended when inflammation is present
- Alternative reporting:
- Antral predominant, corpus predominant or pangastritis
- Focal or diffuse
- Superficial or full thickness
- Atrophy: present or absent
- Metaplasia: present or absent
- Inflammation: active, chronic or both
- H. pylori present or absent
- Biopsies: