CNS tumor
Tumors of the sellar region

Topic Completed: 1 January 2006

Revised: 2 January 2019, last major update January 2006

Copyright: (c) 2002-2017,, Inc.

PubMed Search: Pituicytoma

Nat Pernick, M.D.
Page views in 2019: 1,214
Page views in 2020 to date: 506
Cite this page: Pernick N. Pituicytoma. website. Accessed June 1st, 2020.
Definition / general
  • Also called infundibuloma
  • Rare low grade glioma of sella and suprasellar region
  • May be derived from neurohypophyseal pituicytes (a specialized glial cell of the stalk and posterior lobe of the pituitary gland with supportive role for vasopressin and oxytocin producing neurons)
  • Mean age 48 years, range 30 - 83 years; 6 of 9 were men
  • Visual symptoms, headaches or hypopituitarism
Radiology description
  • Solid, discrete, contrast enhancing masses within sella or suprasellar space
Case reports
  • Total resection
  • May recur if incompletely excised
Microscopic (histologic) description
  • Sheet, fascicles or storiform arrangement of plump bipolar spindle cells with abundant, slightly fibrillar eosinophilic cytoplasm without vacuoles and without granulation, mildly pleomorphic and oval nuclei with pinpoint nucleoli
  • Rich capillary network with vessels often surrounded by radiating spindle cells
  • No infiltration of adjacent tissue, no Rosenthal fibers, no granular bodies, no granular axonal dilations (Herring bodies, normally present in neurohypophysis), no / rare mitotic figures
Microscopic (histologic) images

Images hosted on other servers:

Storiform-like pattern

Positive stains
Negative stains
Electron microscopy description
  • Bipolar spindle cells with abundant intermediate filaments
  • No meningothelial or ependymal features
Differential diagnosis
Additional references
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