Skin nonmelanocytic tumor
Other tumors of skin
Leiomyosarcoma


Topic Completed: 1 September 2012

Minor changes: 15 January 2021

Copyright: 2001-2021, PathologyOutlines.com, Inc.

PubMed search: (cutaneous) leiomyosarcoma [title] skin

Christopher S. Hale, M.D.
Page views in 2020: 1,690
Page views in 2021 to date: 126
Cite this page: Hale C. Leiomyosarcoma. PathologyOutlines.com website. https://www.pathologyoutlines.com/topic/skintumornonmelanocyticLMS.html. Accessed January 22nd, 2021.
Definition / general
  • Malignant smooth muscle tumor similar to counterparts elsewhere
  • Typically larger than leiomyomas with vascular invasion
  • Recurs, but only rarely metastasizes
  • May be associated with HIV infection
Case reports
Microscopic (histologic) description
  • Cellular lesions of smooth muscle type cells with atypia, necrosis and mitotic activity
  • May have prominent vascular pattern, clear cell features, desmoplasia
Microscopic (histologic) images

Images hosted on other servers:

Various images

Positive stains
Back to top
Image 01 Image 02