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General
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Epidemiology
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Sites
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Etiology
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Clinical features
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Diagnosis
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Laboratory
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Radiology
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Prognostic factors
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Case reports
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Treatment
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Clinical images
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Various images

Gross description
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Gross images
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Well circumscribed gray-white tumor

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Well circumscribed multinodular tumor

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Trabecular or whorled appearance resembling leiomyoma

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COW #319, 34 year old man

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Adrenal ganglioneuroma

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Adrenal ganglioneuroma, cut surface

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Composite ganglioneuroma and pheochromocytoma

Micro description
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Micro images
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Case of the Week #319:

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Polygonal tumor cells in well defined nests

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Atypical polygonal chromaffin cells

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Ganglion cells and Schwann cells

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Abundant Schwann cells

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Clusters of ganglion cells

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Ganglion cells surrounded by Schwann cells

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Leydig cells

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Contributed by Professor D. Y. Cohen, Herzliyah Medical Center, Israel: retroperitoneal tumor

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H&E, S100, neurofilament

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Chromogranin

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Neurofilament

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S100

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Vimentin+, synaptophysin+

Virtual slides
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Adrenal gland ganglioneuroma

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Pheochromocytoma with focus
of ganglioneuroma

Cytology description
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Cytology images
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Schwann cells and admixed ganglion cells (insets), neck

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Schwann cells (a, c) and ganglion cells (b, d), neck

Positive stains
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Negative stains
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Electron microscopy description
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Molecular / cytogenetics description
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Differential diagnosis
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End of Adrenal gland and paraganglia > Neuroblastic tumors > Ganglioneuroma



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