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See also: Cutaneous, Epithelioid, Myxoid, Pleomorphic, Rhabdoid features

General
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Epidemiology
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Sites
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Case reports
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Treatment and prognosis
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Clinical images
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12 cm tibial tumor

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Oral cavity tumor

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Epididymis mass (25 cm)

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Internal jugular vein

Gross description
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Gross images
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Leg tumor

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Retroperitoneal tumor

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Thigh tumor

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Bone

Micro description
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Malignant criteria by site
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Micro images
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Spindle cells arranged in interlacing bundles

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Mitotic figures

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Masson trichrome

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Desmin+

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SMA+

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Thigh, moderate nuclear pleomorphism

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Pronounced nuclear pleomorphism

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Foci of coagulative tumour cell

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MIB1

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Retroperitoneum smooth muscle morphology

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Marked pleomorphism, no identifiable smooth muscle

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Epididymis tumor

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Uncertain malignant potential: 8 cm retroperitoneal tumor with bland cells and < 1 MF/10 HPF

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Malignant based on low power pleomorphism

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Pleomorphism and smooth muscle differentiation evident

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Markedly pleomorphic, little evidence of smooth muscle differentiation

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Multinucleated giant cells

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Intravenous tumor

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Inf vena cava tumor: cytology, H&E, smooth muscle actin

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Tibial tumor

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Mediastinal tumor



Images courtesy of Dr. Mark R. Wick

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Deep soft tissue

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Storiform growth

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Retroperitoneal

Cytology description
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Positive stains
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Negative stains
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Electron microscopy description
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Molecular / cytogenetics description
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Differential diagnosis
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End of Soft Tissue > Smooth muscle > Leiomyosarcoma-general



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