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Soft tissue
Fibroblastic / myofibroblastic tumors
Sclerosing epithelioid fibrosarcoma (SEF)

Reviewer: Cliff Sullivan, M.D. (see Reviewers page)
Editor: Jerad M. Gardner, M.D.
Revised: 9 June 2013, last major update June 2013
Copyright: (c) 2002-2013, PathologyOutlines.com, Inc.

Definition
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Epidemiology
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Sites
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Clinical features
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Prognostic factors
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Case reports
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Treatment
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Gross description
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Gross images
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Lobulaulated, multinodular white mass
Micro description
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Micro images
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Figure 1
Figure 2
Figure 3
Figure 4
Fig 1: Nests of epithelioid cells with clear cytoplasm in a background of dense hyalinized stroma
Fig 2: Cords and strands of epithelioid cells with more eosinophilic cytoplasm within densely collagenized matrix
Fig 3: Cords of epithelioid cells within a eosinophilic hyalinized stroma
Fig 4: Epithelioid cells with angulated nuclei, arranged in cords (single-file pattern) with dense sclerotic background
Alveolar pattern
High power with more cellular appearance
Hemangiopericytoma-like vascular pattern
Cytology description
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Positive stains
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Negative stains
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Electron microscopy description
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Molecular / cytogenetics description
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Differential diagnosis
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End of Soft tissue > Fibroblastic / myofibroblastic tumors > Sclerosing epithelioid fibrosarcoma (SEF)


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