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General
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Epidemiology
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Clinical features
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Gross images
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Circumscribed tumor

Micro description
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Micro images
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Tumor cells

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Tumor cells form single files

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Moderate pleomorphism

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Pleomorphic tumor cells

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Florid host response

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Tumor retains discohesive nature

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Large signet ring and plasmacytoid cells

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Cytokeratin staining

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Significant nuclear pleomorphism

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Signet ring type cells

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With pleomorphic LCIS

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Contributed by Dr. Semir Vranic

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Courtesy of Dr. Mark R. Wick

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Pagetoid spread, courtesy of Dr. Mark R. Wick

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In axillary, courtesy of Dr. Mark R. Wick

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Cadherin negative, courtesy of Dr. Mark R. Wick

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E cadherin- (residual normal ducts), Dr. Semir Vranic

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E-cadherin negative

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p53

Cytology description
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Cytology images
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Various images

Positive stains
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LCIS

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With DCIS

Positive stains
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Negative stains
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Molecular / cytogenetic description
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Molecular / cytogenetic images
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HER2 amp, courtesy of Dr. Mark R. Wick

Differential diagnosis
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Additional references
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End of Breast malignant, males, children > Carcinoma subtypes > Pleomorphic variant of lobular carcinoma



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