Skin nonmelanocytic tumor
Lymphoma and related disorders (see also Lymphoma chapter)
Lymphoid hyperplasia
Author: Christopher S. Hale, M.D.
Topic Completed: 1 June 2012
Minor changes: 15 October 2020
Copyright: 2003-2021, PathologyOutlines.com, Inc.
PubMed search: Lymphoid hyperplasia [title]
Table of Contents
Definition / general | Treatment | Clinical images | Gross description | Microscopic (histologic) description | Microscopic (histologic) images | Positive stains | Differential diagnosisCite this page: Hale C. Lymphoid hyperplasia. PathologyOutlines.com website. https://www.pathologyoutlines.com/topic/skintumornonmelanocyticlymphoidhyperplasia.html. Accessed March 5th, 2021.
Definition / general
- Nonspecific finding
- May be due to trauma, infection, arthropods
Treatment
- Rituximab may be useful (Clin Lymphoma Myeloma Leuk 2011;11:286)
Clinical images
Contributed by Mark R. Wick, M.D.
Breast skin
Gross description
- Solitary nodules or plaques
Microscopic (histologic) description
- Lymphocytic and histiocytic infiltrate with tingible body macrophages, plasma cells, eosinophils
- Often germinal cells or lymphoid follicles, hyperplastic vessels or epidermal hyperplasia
- Usually spares epidermis
Microscopic (histologic) images
Contributed by Mark R. Wick, M.D.
Breast skin
Various images
Florid idiopathic
Idiopathic
Differential diagnosis
- MALT lymphoma: marginal zone cells, Dutcher bodies, sheets of plasma cells
