Mediastinum
Cystic lesions
Thymomas - cystic


Topic Completed: 1 December 2012

Revised: 13 February 2019

Copyright: 2003-2018, PathologyOutlines.com, Inc.

PubMed Search: Thymomas cystic mediastinum
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Cite this page: Gulwani H. Thymomas - cystic. PathologyOutlines.com website. http://www.pathologyoutlines.com/topic/mediastinumcysticthymoma.html. Accessed March 20th, 2019.
Definition / general
  • Cystic degeneration of thymoma in anterosuperior mediastinum
Clinical features
  • Associated with paraneoplastic syndromes
Gross description
  • Encapsulated, uniloculated or multiloculated
  • Variable cystic contents
Microscopic (histologic) description
  • Bland proliferation of thymic epithelium (spindle or polygonal cells) present in cyst wall
  • Usually no cholesterol granulomas, no cartilage, no smooth muscle
Microscopic (histologic) images

Images hosted on other servers:

Spindle cell thymoma (type A) has cysts of various sizes

Differential diagnosis
  • Thymic cyst: no / minimal thymic epithelial cells in cyst wall; no evidence of thymoma
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