Cystic lesions
Thymomas - cystic

Author: Hanni Gulwani, M.D. (see Authors page)

Revised: 15 June 2018, last major update December 2012

Copyright: (c) 2003-2018,, Inc.

PubMed Search: Thymomas cystic mediastinum

Cite this page: Gulwani, H. Thymomas - cystic. website. Accessed July 22nd, 2018.
Definition / general
  • Cystic degeneration of thymoma in anterosuperior mediastinum
Clinical features
  • Associated with paraneoplastic syndromes
Gross description
  • Encapsulated, uniloculated or multiloculated
  • Variable cystic contents
Microscopic (histologic) description
  • Bland proliferation of thymic epithelium (spindle or polygonal cells) present in cyst wall
  • Usually no cholesterol granulomas, no cartilage, no smooth muscle
Microscopic (histologic) images

Images hosted on other servers:

Spindle cell thymoma (type A) has cysts of various sizes

Differential diagnosis
  • Thymic cyst: no / minimal thymic epithelial cells in cyst wall; no evidence of thymoma