Skin nonmelanocytic tumor
Adnexal tumors
Sweat gland derived (apocrine & eccrine glands)
Primary cutaneous mucinous carcinoma
Author: Christopher S. Hale, M.D.
Last author update: 1 June 2012
Last staff update: 19 September 2023
Copyright: 2002-2024, PathologyOutlines.com, Inc.
PubMed Search: Mucinous carcinoma [title] skin
Table of Contents
Definition / general | Case reports | Clinical images | Gross description | Microscopic (histologic) description | Microscopic (histologic) images | Positive stains | Differential diagnosisCite this page: Hale CS. Primary cutaneous mucinous carcinoma. PathologyOutlines.com website. https://www.pathologyoutlines.com/topic/skintumornonmelanocyticmucinouscarcinoma.html. Accessed April 20th, 2024.
Definition / general
- Also called adenocystic carcinoma
- Scalp of elderly patients
- Caucasian > Black > Asian
Case reports
- 50 year old woman with gluteal mass (Indian J Pathol Microbiol 2009;52:225)
- 51 year old woman with slowly growing scalp nodule (Case of the Week 413)
- 58 year old Jamaican man with mass on left cheek (Dermatol Surg 2011;37:1192)
Clinical images
Contributed by Mark R. Wick, M.D.
carcclin.jpg)
Gross description
- Slow growing, solitary, asymptomatic, flesh colored nodule with a slightly translucent surface
Microscopic (histologic) description
- Resembles mammary colloid carcinoma with lakes of mucin containing small tumor cell clusters
- May also have an infiltrating ductal pattern
Microscopic (histologic) images
Contributed by Mark R. Wick, M.D., Case #413 and @JMGardnerMD on Twitter
H&E images
CK5/6
CK7
CK20
ER
PR
GATA3
carc2.jpg)
Primary cutaneous mucinous carcinoma
Images hosted on other servers:
Gluteal mass
Differential diagnosis
- Metastatic breast mucinous carcinoma: CK7+, 60% are p63+, otherwise negative (J Cutan Pathol 2010;37:411)
- Metastatic colonic mucinous carcinoma: CK20+
