Skin nonmelanocytic tumor

Adnexal tumors

Sweat gland derived (apocrine & eccrine glands)

Primary cutaneous mucinous carcinoma



Topic Completed: 1 June 2012

Minor changes: 6 November 2020

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PubMed Search: Mucinous carcinoma [title] skin

Christopher S. Hale, M.D.
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Cite this page: Hale CS. Primary cutaneous mucinous carcinoma. PathologyOutlines.com website. https://www.pathologyoutlines.com/topic/skintumornonmelanocyticmucinouscarcinoma.html. Accessed December 4th, 2021.
Definition / general
  • Also called adenocystic carcinoma
  • Scalp of elderly patients
  • Caucasian > Black > Asian
Case reports
Clinical images

Contributed by Mark R. Wick, M.D.
Gross description
  • Slow growing, solitary, asymptomatic, flesh colored nodule with a slightly translucent surface
Microscopic (histologic) description
  • Resembles mammary colloid carcinoma with lakes of mucin containing small tumor cell clusters
  • May also have an infiltrating ductal pattern
Microscopic (histologic) images

Case #413

H&E images

CK5/6

CK7


CK20

ER

PR

GATA3



Contributed by Mark R. Wick, M.D.



Images hosted on other servers:

Gluteal mass

Positive stains
  • Primary skin tumors: 100% CK7+, 40% showed rare p63+ cells, 20% had focal CK5/6+
Differential diagnosis
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