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Case of the Week - by category
Last revised: 19 November 2009
We email subscribers an interesting pathology case with a short discussion three weeks per month. Cases are also posted on these pages. To subscribe, send an email to SubscribePath@gmail.com and indicate “case of the week". There is no charge. We do not sell, share or use your email address for any other purpose, and you can always unsubscribe. These emails may contain advertising, but advertisers do not have access to email addresses. To contribute an interesting case, send an email to KHpathology@gmail.com with images in JPG, GIF or TIFF format, a short clinical history and a diagnosis, as well as your mailing address. If we use the case, we will list you as the contributor and send you $35 (US dollars) by check or PayPal for your assistance.
Cases by category (click here for cases by clinical history)
Table of contents
Breast, cytopathology, dermatopathology, GI, GU, gynecologic, head and neck, hematopathology, liver, lung, microbiology, neuropathology, other, pediatric, soft tissue and bone
Case 68: 84 year old woman with a breast nodule - apocrine carcinoma
Case 62: 22 year old woman with an enlarging breast mass - sclerosing lobular hyperplasia
Case 45: 72 year old woman with lumpectomy for mammographic calcifications - neuroendocrine DCIS
Case 37: 48 year old woman with a mammary fibroadenoma containing atypical cells - fibroadenoma with bizarre stromal giant cells
Case 35: 54 year old woman with large breast mass and nipple discharge - cystic hypersecretory DCIS
Case 25: 61 year old woman with suspicious microcalcifications on mammography - calcium oxalate microcalcifications
Case 11: Postmenopausal woman with a breast mass - colloid (mucinous) carcinoma of the breast
Case 8: 52 year old woman with a breast mass - secretory carcinoma of the breast
Case 6: 66 year old woman with a well circumscribed breast mass - metaplastic carcinoma of the breast
Case 4: 59 year old woman with a breast mass - invasive micropapillary carcinoma of the breast (metastatic to lymph node)
Case 100: 50 year old man with bilateral neck masses - nasopharyngeal carcinoma
Case 72: Two year old boy with multiple skull masses - Langerhans cell histiocytosis
Case 36: 7 year old girl with fine needle aspiration of a chest mass - anaplastic large cell lymphoma
Case 28: Elderly man with a fixed neck mass - adenoid cystic carcinoma of larynx extending to thyroid gland
Case 9: 47 year old man with a pleural based lesion - schwannoma
Case 160: 52 year old woman with chronic, diffuse, lichenified eruptions on leg - scabies
Case 155: 18 year old woman with papules on legs x 12 years, now on hands - Darier’s disease
Case 153: 34 year old woman with papular lesions on hand and face
Case 151: 86 year old man with indurated cutaneous papules - atypical CML with leukemia cutis and vasculitis
Case 140: 68 year old woman with eruption of violaceous skin nodules - leukemia cutis
Case 116: 60 year old man with scalp nodule - epithelioid variant of benign fibrous histiocytoma
Case 113: 24 year old woman with abdominal skin lesion - pigmented epithelioid melanocytoma
Case 107: 37 year old man with skin lesion in the back - retiform hemangioendothelioma
Case 71: 64 year old woman with pruritic, erythematous plaques on her abdomen and back - erythema gyratum repens
Case 56: 85 year old Mexican woman with pruritic and scaly plaques on her trunk - pemphigus foliaceus
Case 7: 19 year old man with lump on wrist - cellular blue nevus
Case 5: 20 year old woman with an “extranumerary nipple” - juvenile xanthogranuloma
Case 161: 18 year old man with abdominal mass and biopsy - hepatocellular carcinoma, fibrolamellar variant
Case 159: 31 year old woman with enlarged stomach lesion - GI histoplasmosis
Case 157: 20 year old woman with dyspepsia - gastric giardiasis
Case 154: 81 year old woman with cystic, papillary pancreatic tumor - IPMN, intestinal type
Case 147: 40 year old man with massive rectal bleeding - inflammatory polyposis
Case 144: 63 year old man with gallbladder tumor - inflammatory MFH or dedifferentiated liposarcoma
Case 143: 37 year old woman with abdominal mass - PEComa
Case 141: 42 year old woman with possible hepatic adenomas - focal fatty change
Case 136: 24 year old woman with a 6 cm cystic pancreatic lesion - acinar cell cystadenoma
Case 134: 10 year old girl with 15 cm liver mass - undifferentiated embryonal sarcoma
Case 133: 43 year old Honduran man with diarrhea and abdominal pain - Stronglyoides stercoralis
Case 129: 52 year old man with anal condyloma - coexisting syphilis
Case 127: 56 year old woman with celiac sprue and nodular areas in the antrum - MALT lymphoma
Case 124: 55 year old man with duodenal polyp - gastric metaplasia/heterotopia
Case 121: 33 year old woman with pancreatic mass - solid pseudopapillary neoplasm
Case 102: 28 year old man had a history of ulcerative colitis - cap polyposis
Case 90: 33 year old woman with clinical appendicitis - Enterobius vermicularis infestation
Case 86: 39 year old woman with a small intestinal mass - inflammatory fibroid polyp
Case 81: 36 year old man with a duodenal mass - follicular dendritic cell sarcoma
Case 33: 48 year old man with a 4 cm gastric mass - gastrointestinal stromal tumor
Case 22: 51 year old man with symptomatic anemia and gastric masses - metastatic renal cell carcinoma
Case 13: 31 year old woman with a pancreatic mass - desmoplastic small round cell tumor of pancreas
Case 145: 15 year old boy with paratesticular tumor - spindle cell embryonal rhabdomyosarcoma
Case 137: 72 year old man with a radical prostatectomy for prostatic adenocarcinoma - prostatic melanosis
Case 131: 76 year old woman with hematuria - malakoplakia of bladder
Case 128: 29 year old man with hydronephrosis - renal tuberculosis
Case 126: 19 year old man with hypertension and renal insufficiency - preB acute lymphoblastic leukemia / lymphoma
Case 122: 43 year old man with testicular tumor - Leydig cell tumor
Case 117: 70 year old man with prostatectomy - pseudohyperplastic variant of prostatic adenocarcinoma
Case 106: 35 week fetus with distended abdomen - meconium peritonitis
Case 94: 57 year old man with tumor of renal pelvis - signet ring cell adenocarcinoma
Case 85: 66 year old man with a radical prostatectomy for prostatic adenocarcinoma - bilateral seminal vesicle amyloidosis
Case 83: 72 year old woman with renal pelvis mass - mixed epithelial and stromal tumor
Case 76: 49 year old man with an inguinal mass - tubulocystic clear cell carcinoma of prostate *with femoral nodal metastases
Case 69: 34 year old man with a scrotal abscess - epithelioid sarcoma
Case 57: 3 month old girl with kidney mass - congenital mesoblastic nephroma
Case 51: 56 year old man with large, cystic renal lesion - tubulocystic carcinoma
Case 48: 50 year old woman with well encapsulated renal mass - papillary renal cell carcinoma, solid variant
Case 43: 44 year old man with a 1 mm incidental renal mass at nephrectomy - papillary adenoma
Case 40: 56 year old man with B cell CLL, post-treatment for a relapse, now with dysuria and hematuria - BK polyoma virus related hemorrhagic cystitis
Case 32: 44 year old woman with incidental renal mass composed of straplike cells - atypical epithelioid angiomyolipoma
Case 30: 41 year old man with diabetes and renal failure after an upper respiratory infection - diabetic nodular glomerulosclerosis with superimposed post - infectious glomerulonephritis.
Case 26: 29 year old man with a testicular mass - mixed germ cell tumor
Case 19: 40 year old woman with large renal mass - monophasic synovial sarcoma
Case 18: 23 year old man with pain in the right testis - sclerosing Sertoli cell tumor
Case 162: 9 month old girl with imperforate anus and presacral mass - teratoma associated with Currarino syndrome
Case 152: 54 year old woman with pelvic mass - metastatic pulmonary adenocarcinoma to ovary
Case 146: 51 year old woman with vaginal polyp - tubulovillous adenoma
Case 135: 50 year old woman with vaginal bleeding - glial polyp of cervix
Case 125: 62 year old woman with post-menopausal bleeding - metastatic lobular carcinoma to a tamoxifen-associated endometrial polyp
Case 109: 58 year old woman with post-menopausal bleeding - melanoma of uterus
Case 96: 55 year old woman with a pelvic mass - adult granulosa cell tumor
Case 92: 59 year old woman with a vaginal discharge - leiomyosarcoma of cervix
Case 91: 44 year old woman with CIN II-III - isolated cervical polyarteritis nodosa
Case 60: 45 year old woman with menometrorrhagia - endometrial intraepithelial neoplasia
Case 59: 7 year old girl with precocious puberty and ovarian mass - juvenile granulosa cell tumor
Case 55: 50 year old woman with an ileocecal mass - endometriosis
Case 53: HIV positive woman from Ghana with large vulvar mass - hypertrophic herpes simplex virus in HIV positive patient
Case 31: 44 year old woman with extensive tumor deposits on the omentum, uterus, tubes and ovaries - serous psammocarcinoma
Case 12: 22 year old woman with an ovarian mass - dysgerminoma
Case 156: 50 year old man with erythematous gingiva - plasma cell gingivitis
Case 142: 17 year old woman with floor of mouth tumor - osseous choristoma
Case 139: 53 year old man with bipolar disorder and sudden death - lithium thyroiditis
Case 138: 51 year old man with a nasal turbinate mass - angioleiomyoma
Case 115: 61 year old man with eyelid swelling - cysticercosis
Case 112: 76 year old man with nasopharyngeal mass - Warthin’s tumor
Case 108: 86 year old woman with neck pain and difficulty swallowing - ectopic parathyroid tissue
Case 104: 22 year old man with fine needle aspiration of a neck nodule - meningioma
Case 103: 86 year old man with stable parotid mass - sebaceous lymphadenoma
Case 101: 40 year old woman with nasal mass - NK/T cell lymphoma
Case 100: 50 year old man with bilateral neck masses - nasopharyngeal carcinoma
Case 97: 29 year old man from India with nasal mass - Rhinosporidiosis
Case 84: 58 year old woman with chronic sinusitis - sinonasal hemangiopericytoma
Case 82: 57 year old man with papillary lesions on his palate - verruciform xanthoma
Case 73: 66 year old man with a cyst-like lesion of the mandible - primary intraosseous odontogenic verrucous carcinoma
Case 54: 59 year old woman with a slow growing parotid mass - epithelial-myoepithelial carcinoma
Case 49: 68 year old woman with large soft palate tumor - sialolipoma of soft palate
Case 42: 63 year old man with painful cheek mass - acinic cell carcinoma of parotid gland
Case 28: Elderly man with a fixed neck mass - adenoid cystic carcinoma of larynx extending to thyroid gland
Case 24: 43 year old man with chronic sinusitis and a nasal polyp - respiratory epithelial adenomatoid hemartoma
Case 14: 17 year old woman with loosening of lower incisors - central giant cell granuloma of mandible
Case 151: 86 year old man with indurated cutaneous papules - atypical CML with leukemia cutis and vasculitis
Case 140: 68 year old woman with eruption of violaceous skin nodules - leukemia cutis
Case 130: 27 year old woman with a swelling of the fibula - myeloid sarcoma
Case 127: 56 year old woman with celiac sprue and nodular areas in the antrum - MALT lymphoma
Case 120: 88 year old woman with abnormal CBC - B cell prolymphocytic leukemia
Case 118: 60 year old man with lower leg edema - angiomyomatous hamartoma of lymph node
Case 101: 40 year old woman with nasal mass - NK/T cell lymphoma
Case 95: 55 year old man with a nodular patch in the cecum at colonscopy - hairy cell leukemia
Case 93: 63 year old woman with axillary mass - Castleman’s disease-hyaline vascular variant
Case 89: 22 year old woman with cervical adenopathy and no other medical history - Kikuchi’s disease
Case 87: 41 year old HIV+ man with pancytopenia and skin nodules - Leishmaniasis
Case 81: 36 year old man with a duodenal mass - follicular dendritic cell sarcoma
Case 79: Elderly man with an enlarged supraclavicular lymph node - CLL/SLL, paraimmunoblastic variant
Case 74: 65 year old woman with backache, abnormal plasma cells but a normal serum protein electrophoresis - light chain multiple myeloma
Case 41: 72 year old woman with multiple strokes - intravascular lymphoma
Case 36: 7 year old girl with fine needle aspiration of a chest mass - anaplastic large cell lymphoma
Case 27: 22 year old woman with worsening pelvic pain - chronic myelogenous leukemia
Case 21: 64 year old Japanese woman with multiple opportunistic infections - adult T cell leukemia / lymphoma
Case 2: Incidental splenic mass during laparoscopy for excision of benign pancreatic cyst - splenic hamartoma
Case 1: 46 year old man with mediastinal mass - follicular dendritic reticulum cell tumor / follicular dendritic cell sarcoma
Case 88: 13 month old girl with incidental liver mass - focal nodular hyperplasia
Case 70: 47 year old woman with a multilocular hepatic cyst - mucinous biliary cystadenoma
Case 61: 15 month old boy with an asymptomatic liver mass - mesenchymal hamartoma
Case 44: 20 year old woman with liver mass identified after childbirth - inflammatory pseudotumor
Case 105: 6 year old boy with bilateral pulmonary infiltrates - acute eosinophilic pneumonia
Case 58: Term newborn with abnormal fetal ultrasound and lobectomy - congenital cystic adenomatoid malformation, type II
Case 23: 80 year old man with a lung nodule and enlarged mediastinal lymph nodes - epithelioid angiosarcoma
Case 9: 47 year old man with a pleural based lesion - schwannoma
Case 133: 43 year old Honduran man with diarrhea and abdominal pain - Stronglyoides stercoralis
Case 87: 41 year old HIV+ man with pancytopenia and skin nodules - Leishmaniasis
Case 53: HIV positive woman from Ghana with large vulvar mass - hypertrophic herpes simplex virus in HIV positive patient
Case 40: 56 year old man with B cell CLL, post-treatment for a relapse, now with dysuria and hematuria - BK polyoma virus related hemorrhagic cystitis
Case 119: 17 year old woman with intraventricular mass - central neurocytoma
Case 111: 71 year old man with filum terminale mass - myxopapillary ependymoma
Case 75: 57 year old man with a CNS intraventricular mass - subependymoma
Case 39: 16 year old girl with new onset of seizures and a temporal lobe mass - pleomorphic xanthoastrocytoma
Case 38: 54 year old man with von Hippel Lindau disease and a cerebellar mass - hemangioblastoma
Case 150: 37 year old woman with pericardial mass - synovial sarcoma
Case 114: 47 year old woman with left ventricular mass - leiomyosarcoma
Case 99: 70 year old man with mediastinal mass - thymoma
Case 98: 18 year old man with pigmented thyroid gland at autopsy - black thyroid due to minocycline
Case 78: 65 year old woman with a left atrial mass - cardiac myxoma with glandular differentiation
Case 17: 61 year old woman with a mediastinal mass - thymic carcinoma
Case 162: 9 month old girl with imperforate anus and presacral mass - teratoma associated with Currarino syndrome
Case 123: 1 year old boy with neck mass - lipoblastoma
Case 106: 35 week fetus with distended abdomen - meconium peritonitis
Case 72: Two year old boy with multiple skull masses - Langerhans cell histiocytosis
Case 67: 2 year old with an abdominal mass - neuroblastoma
Case 59: 7 year old girl with precocious puberty and ovarian mass - juvenile granulosa cell tumor
Case 58: Term newborn with abnormal fetal ultrasound and lobectomy - congenital cystic adenomatoid malformation, type II
Case 57: 3 month old girl with kidney mass - congenital mesoblastic nephroma
Soft tissue and Bone pathology
Case 158: 26 year old woman with mass on palm of hand - lipomatosis of nerve
Case 149: 50 year old woman with thigh mass - parachordoma
Case 145: 15 year old boy with paratesticular tumor - spindle cell embryonal rhabdomyosarcoma
Case 132: 54 year old woman with supraclavicular mass - DFSP, myxoid variant
Case 130: 27 year old woman with a swelling of the fibula - myeloid sarcoma
Case 123: 1 year old boy with neck mass - lipoblastoma
Case 110: 47 year old man with low back pain - chordoma
Case 107: 37 year old man with skin lesion in the back - retiform hemangioendothelioma
Case 80: 28 year old man with a red thigh nodule for 6 months suggestive of Kaposi’s sarcoma - microvenular hemangioma
Case 77: 55 year old man with a large thigh mass - epithelioid hemangioendothelioma
Case 72: Two year old boy with multiple skull masses - Langerhans cell histiocytosis
Case 66: 71 year old man with a popliteal fossa mass - synovial chondromatosis
Case 65: 37 year old woman with a wrist mass - nodular fasciitis
Case 64: 55 year old bedridden man with a hip mass - ischemic fasciitis
Case 63: 53 year old man with a recurrent, painful pretibial mass - phosphaturic mesenchymal tumor
Case 52: 33 year old man with an asymptomatic hand mass - chondroid lipoma
Case 50: 12 year old girl with superficial nodular tumor of back - superficial plexiform schwannoma
Case 47: 16 year old girl with tumor of foot - calcifying aponeurotic fibroma
Case 46: Elderly individuals with scapular masses - elastofibroma
Case 34: 24 year old man with an inguinal soft tissue discharging chalky fluid - tumoral calcinosis
Case 29: 33 year old woman with soft tissue mass of cheek - solitary fibrous tumor of dermis
Case 20: 22 year old man with Mafucci’s syndrome and painful swellings of hands and feet - spindle cell hemangioma
Case 16: 56 year old man with a retroperitoneal mass - lipomatous hemangiopericytoma
Case 15: 62 year old man with a slowly enlarging thumb mass - aggressive digital papillary adenocarcinoma
Case 10: 30 year old man with a thigh lesion - high grade myxoid / round cell liposarcoma
Case 3: 90 year old woman with recurrent soft tissue tumor from the ankle region - sclerosing epithelioid fibrosarcoma
End of Case of Week by Category page